In this prospective follow up study we evaluated and compared the effect of arthroscopic lavage with and without debridement as a treatment of moderately osteoarthritic knees in middle aged and elderly population. The study group comprised of 500 patients (250 patients for each type of treatment, mean age 58 years). The patients were followed six months, three years and six years postoperatively. Following both treatments there was a clear deterioration in function of the knee function over the time, as measured starting at six months follow up until six years postoperatively (p < 0.001). This deterioration was more prominent in patients after treatment by the arthroscopic lavage only. We show that for the patients with high functional demand and expectations for long term rehabilitation and improvement both arthroscopic treatments are not satisfactory in more of 60% of cases.
Degenerative arthritis (Osteoarthritis, OA) of the knee is a common cause of knee pain. The pain from osteoarthritis is due to synovitis, capsular and ligamentous inflammation, and subchondral bone edema.
OA is commonly the end result of abnormally distributed mechanical stress on the articular cartilage, either through a sudden single load or following a cumulative effect of multiple and/or repetitive loads that lead to mechanical disintegration of the structure of hyaline cartilage.
The treatment of knee pain due to OA is usually directed to oppose the causative abnormal articular mechanics, e.g. conservative treatment by rest, weight loss, physical therapy for strengthening thigh musculature and subsequentially reducing intrarticular forces; pharmacological treatment by nonsteroidal anti-inflammatory drugs or steroid injections in order to reduce local inflammation and surgical treatment, i.e. arthroscopic in order to debride superficial cartilage irregularities and induce new cartilage generation by deep subchondral exposure or aiming to correct the joint deformity by corrective osteotomy [
Usually when the conservative options fail, arthroscopic debridement and lavage are rationally considered because of the less morbid outcome of this procedure [
Arthroscopic debridement of the degenerative knee is a common surgical procedure and could be beneficial in patients with symptomatic knee OA but without an extensively damaged articular surface. Arthroscopic debridement can be done as an outpatient procedure, because of its low postoperative morbidity. Following this type of surgery early return to the normal daily activities is expected. Therefore the rationale for offering arthroscopic debridement in the mild cases of knee OA is due to expected rapid improvement in symptoms and function without serious postoperative morbidity [
This is a prospective follow up study. Between 1998 to 2007, five hundred patients underwent arthroscopic surgery for the treatment of knee OA .This patient group suffered from knee pain on effort, had radiographic evidence of minor to moderate joint space narrowing and marginal osteophyte formation (
In this group 250 patients underwent arthroscopic debridement and lavage, and additional 250 patients underwent arthroscopic lavage only. The arthroscopic debridement included debridement and shaving of osteoarthritic articular cartilage and of degenerative meniscal lesions.
Patients with inflammatory arthritis, severe misalignment of knee (valgus greater than 10 degrees or varus greater than 5 degrees), those with large meniscal tears or with radiographic evidence of the end stage OA and when a lack of full knee extension was evident were excluded from the study. The mean age of the patients at the time of surgery was 62 years (range, 52 to 78 years). For the purpose of this study each patient was evaluated six months after surgery and then after 3 years and six years postoperatively.
In all patients the arthroscopies were performed under local anesthesia by injecting through the routine portals into the knee joint of 10 cc of lidocaine 2% and 20 cc of bupivacaine 0.25%. Tourniquet was not used. The arthroscopic findings, including the condition of articular cartilage, meniscal lesions and ligamentous insufficiency, were all recorded. All the surgeries were done by one of the authors (KS) and the study was approved by the Institutional Ethical Committee.
The modified Hospital for Special Surgery (HSS) scoring scale [
The statistical comparison of the results was according to Chi Square test from contingency tables, P values below 0.05 determined the significant difference between the values [
There were no deep infections or superficial wound problems, no deep vein thrombosis and no other major complications.
Twenty patients were lost to follow up at 6 months (9 from the “lavage only” group), additional 9 patients at 3 years (7 from the “lavage only” group) and 11 patients were lost to follow up at 6 years (5 from the “lavage only” group). Therefore 8%, 2%, and 2% of patients were lost on the three stages of follow up respectively.
On initial short term postoperative follow up most of the patients from two treatment groups showed similar positive outcome, i.e. good and excellent knee function in 66% and 77% of patients after lavage only and debridement and lavage treatment respectively, with overall better outcome results in patients after debridement and lavage treatment (p < 0.01,
At midterm follow up, three years postoperatively, the outcome in the lavage only group was completely opposite to the initial short term evaluation, i.e. 69% of these patients showed poor knee function and only 21% of patients showed good and excellent function (p < 0.001,
At long follow up of 6 years most of the patients in two groups had poor knee function, 84% of patients after lavage treatment and 64% of patients after debridement and lavage treatment, but still with overall better outcome in patients of the latter group with almost double rate of good and excellent results, 25% after debridement and lavage vs. 12% after lavage only group (p < 0.001,
Overall following both treatments there was a clear deterioration in function of the knee over the time, as measured starting at six months follow up to six years postoperatively (p < 0.001,
Both, arthroscopic lavage and arthroscopic lavage and debridement, are relatively conservative salvage approach to moderately degenerative knee in old population. There is a controversy if these treatments are advantageous to conservative treatment or to more extensive treatment by prosthetic arthroplasty in older population.
There are reports that might support this conservative treatment, e.g. McLaren et al. found 65% improvement of symptoms after arthroscopic debridement of arthritic knees after short, average 2 years, follow-up [
four years’ follow up following arthroscopic debridement of degenerative knees [
In the present large scale study we confirm relatively satisfactory results at midterm follow up (3 years) following debridement and lavage of moderately arthritic knees but on the long term follow up (6 years) we observed a significant deterioration of knee function in these patients. Additionally the treatments by arthroscopic lavage only showed unsatisfactory results even after midterm follow up. Therefore we show that arthroscopic lavage only treatment should not be suggested to patients that expect at least midterm improvement in symptoms.
Additionally we can conclude from our results that only a selected group of patients with expectation for short term (of several months) relief of knee symptoms might benefit from arthroscopic knee lavage with a benefit of low surgical morbidity.
For the patients with higher demands and expectations for long term rehabilitation and improvement both arthroscopic treatments are not satisfactory in more of 60% of cases.
The presented data in a large series of patients provide an important tool in the decision making and tailoring of the surgical procedure for the patients with moderate symptomatic OA of knee, who have different expectations from surgical treatment on short, midterm and long term period of time.