Received 5 October 2015; accepted 22 October 2015; published 28 October 2015

ABSTRACT

Introduction: Ascariasis by Ascaris lumbricoides is a cosmopolitan disease. Biliary ascariasis is unusual in our country. We report a case of biliary ascariasis revealed by biliary colic. Observation: A 22-year-old woman with no particular history was received for biliary colic associated to vomiting without fever or bowel disorders. On examination, there were pain and defense at the right upper quadrant and a Murphy sign. Moreover, the clinical examination was normal. Blood cells count, renal function, liver function, coagulation and blood ionogram were normal. The abdo- minopelvic ultrasonography showed a probable parasitosis of the bile duct with gallbladder sludge and dilatation of the common bile duct. The abdominopelvic CT scan revealed intrahepatic and common bile duct (CBD) dilatation and organic image in the common bile duct. Right sub- costal laparotomy was allowed to extract an ascaris blocking the common bile duct. A cholecys- tectomy and drainage of the bile duct with a Kehr drain were performed. The postoperative course was marked by wound surgical suppurative resolved by treatment. She was discharged on the 9^th post-operative day. T-tube was removed on the 21^st post-operative day after normal cho- langiography. Conclusion: Biliary ascariasis is rare in our regions. The diagnosis must be kept in mind in case of biliary colic and ultrasound confirm the diagnosis. Surgical treatment gives good results in our regions.

Keywords:

Ascariasis, Biliary Ascarisis, Cholecystitis, Pancreatitis, Cholangitis

Subject Areas: Surgery & Surgical Specialties

1. Introduction

Ascariasis by Ascaris lumbricoides is a cosmopolitan disease, especially in hot and humid low-income countries [1] . Biliary ascariasis is rare in our regions. However, it is common in India where it is endemic in the Kashmir Valley [2] [3] . Biliary ascariasis symptomatology is variable, ranging from a biliary colicto cholangitis. Ultrasound has a very good sensitivity for the diagnosis [4] . We report a case of biliary ascariasis revealed by biliary colic.

2. Case Report

A 22-year-old woman without particular history presented at our emergency unit for a right upper quadrant pain, blocking breathing associated with vomiting without fever or bowel disorders. The temperature was 37.7˚C, pulse rate 98 beats/mn, respiratory rate 24 cycles/mn and blood pressure 110/70 mmHg. There were pain and defense at the right upper quadrant with a Murphy sign. Moreover, the clinical examination was normal. The white blood cells rate was 7800/mm³, hemoglobin’s rate 14.7 g/dl, platelet’s rate 287000/mm³ and hematocrit 46%. The renal function, liver function, coagulation, and blood ionogram were normal. The abdominopelvic ultrasonography showed a probable parasitosis of the bile duct extended to the upper biliary confluence with gallbladder sludge and dilatation of the common bile duct to 13 mm (Figure 1). The abdominopelvic CT scan showed an intra and extrahepatic duct dilatations and tissular image in the common bile duct (Figure 2). Right subcostal laparotomy exploration showed gallbladder and main bile duct dilatation. Cholecystectomy and longi- tudinal choledocotomy allowed to extract a living female worm measuring 20 cm long obstructing the common bile duct. We extracted the worm through the incision and performed a common bile duct drainage with a Kehr drain (Figure 3 and Figure 4). She was treated by albendazol 400 mg per day during 3 days. The postoperative course was marked by surgical wound infection well treated with antibiotics and daily dressings. Kehr drain was clamped to 9^th postoperative day. She was discharged on 12^th postoperative day. Cholangiography by the T-tube was performed at 21^st postoperative day without abnormalities allowing the removal of the drain (Figure 5).

3. Discussion

Biliary ascariasis is rare in our regions. It can be found at any age but especially in children and young adults as in our patient [5] - [7] . The migration of Ascaris lumbricoides in the biliary ducts is the most common surgical complication of ascariasis [6] . According to Sandouk F. et al., in patients with biliary ascariasis, cholecys- tectomy and endoscopic sphincterotomy are risk factors accounting respectively in 80% and 77% [1] . Endoscopic

sphincterotomy induced sphincter of Oddi relaxation promoting migration of worm into the biliary tree. The symptoms are variable. Its diagnosis may be accidental during ultrasonography or cholecystectomy [6] . It can be revealed by recurrent biliary colic, cholecystitis, cholangitis, liver abscesses and pancreatitis [1] [6] . The death of roundworms in the bile duct may lead to inflammation of the mucosa then a stricture [6] . It raises the differential diagnosis with gallstone disease especially in our regions where it is rare. The particularity in our patient was an inaugural picture at the stage of biliary obstruction. Eosinophilia oriented towards parasitosis without specifying the site. The certitude diagnosis is made in case of detection of the parasite in the stool or in the duodenum during endoscopy [6] . In endemic countries like India, the diagnosis is made by clinical examination, ultrasound and endoscopy [6] . In our patient, the diagnosis was early made by clinic examination and ultrasound. Ultrasound made the diagnosis by showing a linear or curvilinear echogenic structure, single or multiple tube with a central void like spaghetti, without posterior shadowing as found in our patient [5] [8] . There are also dilatation of intra and extrahepaticbiliary ducts. Roundworm can also appear as a pseudotumor [5] [8] . CT scan is used to exclude liver and pancreatic pathology in cases of indirect signs of dilatation of the bile duct. However, on CT scan and ultrasound, the main differential diagnosis are tumors and gallstones [6] . Medical treatment consisted on diet, intravenous administration of antibiotics and antispasmodics to remove the round worm of the biliary tract [4] . In case of medical treatment, anthelmintics should not be administered because they could lead to roundworms death in the bile duct [6] . Persistent clinical signs after 72 hours of medical treatment indicated performing endoscopy or surgery [6] . The endoscopic retrograde cholangiopancreagraphy (ERCP) is an excellent therapeutic mean for extracting roundworm through the duodenal papilla with a high rate of success and low complication rates [1] [4] [6] . Surgery is indicated in case of failure of endoscopic treatment, of liver abscesses, gallbladder roundworms, intrahepatic roundworm and severe acute pancreatitis. Procedure will consist of cholecystectomy, choledocotomy with worm extraction and drainage of the bile duct with a T-tube as performed in our patient. Some authors provide biliary bypass such as choledocho-duodenostomy, choledocho-jejunostomy, hepatico-jejunostomy. In rare cases of intra-hepatic ascarisis, hepatectomy may be indicated [2] [3] . Surgical treatment in our patient was justified by the unavailability of ERCP.

4. Conclusion

Biliary ascariasis is rare in our regions. The diagnosis should be kept in mind in case of biliary colic. Ultrasound is a good tool diagnosis in low-income countries. Surgical treatment is a good indication in our regions.

Conflict of Interest

None declared.

Cite this paper

Ousmane Thiam,Mohamadou Lamine Gueye,Alpha Oumar Toure,Mamadou Seck,Lera Geraud Akpo,Hamidou Deme,Mamadou Cisse,Ousmane Ka,Madieng Dieng,Abdarahmane Dia,Cheikh Tidiane Toure, (2015) Biliary Ascariasis: An Unusual Cause of Biliary Colic. Open Access Library Journal,02,1-5. doi: 10.4236/oalib.1102003

References

NOTES

^*Corresponding author.