L. M. DA SILVA ET AL.
188
finding is that few residual amounts cannot be easily de-
tected by ultrasound examination and this might have
influenced the interpretation of the results.
Diurnal variation in diuresis is another factor that has
been suggested to interfere with CrCl-2h assessment.
However, creatinine clearance estimates obtained at a
shorter interval (8 hours) have been demonstrated to be
as accurate as 24-h clearances [16].
In conclusion, two-hour creatinine clearance was not
an adequate substitute for GFR estimates based on crea-
tinine and cystatin C serum levels in older patients at
preoperative period. The ultrasonic assessment of resid-
ual bladder volume had no significant influence on the
calculation of two-hour creatinine clearance.
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