Aim: To report a rare case of spontaneous bilateral pneumothorax with recurrent pneumothorax. Background: Spontaneous bilateral pneumothorax is medical and surgical emergency. It is presence of free air in the bilateral pleural spaces. It rarely occurs at any age but usually young age without apparent precipitating etiology in healthy subjects without any existing pathology. Case Report: In present case, a non smoker, uneducated, young housewife was received in emergency in critical condition and admitted in Intensive Care Unit directly, Peoples Medical university Hospital, Nawabshah, and Sindh, Pakistan. She felt difficulty in breath and after few moments she complained chest pain on right side of chest. They rushed in emergency in Peoples Medical University hospital and diagnosed as case of pneumothorax and at the same time her symptoms started worsening and she developed central cyanosis. In emergency chest X-ray was done showing bilateral pneumothorax, patient developed respiratory distress, emergency bilateral chest intubation was done and due to SO2 drop. Patient was kept on mechanical ventilation. After 24 hours she was weaned off and she was vitally in stable state and shifted in medical department and after 2 weeks she was discharged well. After 3 days of discharge she again came in emergency X-ray shown right sided recurrent pneumothorax, chest intubation done and she was referred to Oojha Institute of Chest Diseases, Karachi, Pakistan for further management and Pleurodesis. Conclusion: Bilateral spontaneous pneumothorax is medical and surgical emergency, diagnosis is thru clinical history, examination of chest and X-ray chest. Prompt diagnosis and management with chest intubation bilaterally and supportive treatment may decrease the morbidity in these critical cases.
Spontaneous pneumothorax common respiratory disorder, resulting in distressful respiration, can be associated with high mortality in certain situations. Spontaneous pneumothorax occurs bilaterally and at the same time accounts about 1.3 percent cases generally [
A 27 years female, married housewife, resident of rural Nawabshah, of average height and mildly overweight presented in Emergency Unit at Medicine Department admitted in intensive care unit due to sudden onset of difficulty in breathing and pain in chest, she was in usual state of health and sitting position without any routine activity. She rushed in emergency room immediately, and chest X-ray done at bed side and surprise to see bilateral pneumothorax (
sudden onset of shortness breath. Chest X-ray showed again right sided pneumothorax (
improved vitally and after stabilization all routine necessary investigations were sent to laboratory.
Past history: no medical surgical or trauma history. Nothing important noted in history. She was not addicted, no history of allergy, blood transfusions, travel, vaccination history not clear. Her menstruation cycle was 03 days/15 days, twice in month, she has 3 children’s all were quite healthy. No such a positive family history for diseases. Diet exercise history was not significant clinically.
Patient was in gasping at the time of admission in ICU. Pulse was not recordable, blood pressure not recordable, cyanosis was positive, SO2 was 65% on pulse oximetery, absent breathe sounds bilaterally. After stabilization rest of other systematic examinations were performed and no abnormal finding detected.
X-ray chest were advised at different stages of management, first at the time of admission (
Viral markers of HBV, HCV, and HIV were advised. HCV antibodies were positive but HCV RNA by PCR was negative. MP ICT antigen was negative. Complete blood count was within normal limits. Blood CBC: RBCs were 4.78 mil/cumm, (Hemoglobin 12.1 g%, ESR 18 mm/hr, HCT 38.8%, MCV 81.2 fl, MCH 28.7 pg, MCHC 35.7 g/dl). WBC 6800/cumm, (Neutrophil 55, Lymphocytes 42, Esinophils 02, Monocytes 01, Basophils 00). Platelets count was 240,000 cumm. Liver chemistry was within normal limits (Billurubin Total = 0.76 mg%, Billurubin direct = 0.24 mg%, Billurubin indirect = 0.52 mg%, SGPT = 41.6 u/l, Alkaline Phosphatse = 192.8 u/l, g-GT = 17.5 u/l). Antibodies against H. pylori antigen were negative. Random Blood Sugar was 94.6 mg/dl, serum Creatinine value was 0.8 mg/dl, and blood urea level was 64/dl, sodium 128 meq/dl, potassium 4.2 meq/l, Chloride 72 mmol/l and HCo3 25 mmol/l. Prothrombin Time 14 Seconds, Control = 14 seconds. Activated Prothrombin Time was 35 seconds, control = 35 seconds. Mountax Test was negative.
Ultrasound: Abdomen and pelvis was normal except bilateral ovarian cysts 3.8 × 3.2 cm in left and 4.4 × 2.3 cm in right.
CT scan chest: Multiple axial scan of 5 mm thickness right sided pneumothorax (after bilateral chest intubations) left sided inflated but on right side there was still incomplete inflation with pneumothorax. No any evident pathology was reported after computed tomographic scan of chest.
Pleural Biopsy: (DOW LAB) 0.5 × 0.5 × 0.2 cm specimen submitted for biopsy in single cassette. Microscopic features: section had shown skeletal muscle fibers, single fragment shown Histiocytic Cell collections and few Foreign Body Giant Cells, no convincing Granuloma seen.
Conclusion: Skeletal muscle fibers with focal Histiocytic cell collections and foreign body giant cell reaction.
Pus Swab culture: Pus for culture from chest intubation shown no bacterial growth.
Pneumothorax defined as clinical and radiological state in which free air accumulates in between pleural layers, resulting in difficulty in breathing and pain in chest due to incomplete or complete collapse of the lung. The X-ray chest is immediate diagnostic tool. This was also a main best initial investigation in present case. Immediate management is chest tube placement for the drainage of air and symptomatic relief. In present case emergency chest tube placement was also done. It may be Primary spontaneous pneumothorax without any apparent recurs in up to 50% of people due to bleb rupture. In spite of many investigations no final diagnosis was made in current case. Pneumothorax occurring spontaneously in patients having pulmonary pathology like obstructive airway disorders is usually due to secondary causes, it can also occur because of other pulmonary diseases like bronchial asthma, pulmonary abscesses, chronic infections like pulmonary tuberculosis, HIV associated pneumonia (Pneumocystis carani), cystic disease of lungs, acute and chronic pneumonitis, infiltrative diseases, pulmonary sarcoid disease and langerhan cell (histiocytosis) disorders. There was no possible etiology concluded in present case. Pneumothorax which is usually spontaneously secondary there is adverse clinical presentation along with outcome. The rate of recurrence rate is similar for both types of pneumothorax (spontaneous primary & secondary).
Secondary spontaneous (catamenial pneumothorax) can rarely be seen within 48 hours of menstruation onset in premenopausal females and may occur in females who use estrogen after menopause. In present case menstruation history was not in favour of catamenial pneumothorax. Traumatic pneumothorax can result due to traumatic chest injury or during some medical procedures as bronchoscopy, thoracoscopy or thoracocentesis where air escapes into the pleural space. There was no such history in current scenario. Ventilators may damage lungs and can direct to pneumothorax usually in patients with COPD or ARDS. Deep-sea drivers and aeroplane pilots are more prone to develop pneumothorax due to changes in the lung pressures (barotrauma) [
Clinical features may be from asymptomatic to tension pneumothorax, critically life threatening condition, unconsciousness, cyanosis and tachyarrhythmia. Management includes aspiration by needle, percutaneous drainage by catheter and thoracotomy [
Hatta et al. reported such a case in which they initially performed the bilateral tube thoracotomy followed by thoracotomy with axillary incisions on both sides with excellent results [
In the presenting case CT chest did not reveal any abnormality. Left lung completely re-expanded and there was partial re-expansion of right lung. This patient underwent surgical Thoracoscopy with right sided chemical Pleurodesis and there were no significant post procedure pulmonary edema.
No etiology was concluded in this case, she was not pregnant at time of illness, no history of chest abdomen trauma, thrusting, and no weight lifting before or at the time of illness.
In present case Computed tomography of the chest revealed no significant pathology. Right sided chest Thoracoscopy with Pleurodesis was done and no immediate or late complication of intervention seen, especially edema due to re-expanded lung tissues. Post procedure X-ray chest shown partial remnants of pneumothorax on right side of chest. In present case the above treatment options were used chest intubation in first episode and Thoracoscopy and Pleurodesis in the recurrent pneumothorax. Although the reason of recurrence was not determined in our case but major steps were to control the situation. From the facts of above case scenario it is evident that in early management placement of chest tube is vital step of management to save the life of patients in bilateral pneumothorax. Efforts should be taken to assess the etiology of the condition. If cause is evident through investigations, steps should be taken to treat it properly. If there is risk of recurrence so the Pleurodesis option should be available as alternative part of management as it was done in this present case. In current case emergency steps were taken for chest intubation and life of patient was secured. No exact etiology was detected in our case. CT scan of chest was almost normal. Thoracoscopy had done no pathology seen. Pleural biopsy was not conclusive. There was incomplete expansion of right lung even after trial of Pleurodesis. No proper diagnosis was made till Pleurodesis. Now the patient is in stable state and living normal limited routine life activities. Present case was managed with initial bilateral chest intubations and broad spectrum antibiotics and lastly on the pleurodesis along with symptomatic treatment. She was advised for follow-up properly. Now she is stable passing her routine life with precautions like not to lift weight, avoid constipation and proper treatment of chest infection if it occurs etc.
Spontaneous Bilateral Pneumothorax, a medical and surgical life-threatening emergency, early diagnosis and emergent management, is crucial step to save the lives of patients and thereby reduces the morbidity and mortality.
Jamali, A.A., Jamali, G.M., Tanwani, B.M., Jamali, N.H., Jamali, A.A. and Rajput, A.A. (2018) Spontaneous Bilateral Pneumothorax with Recurrent Pneumothorax: A Case Report. Case Reports in Clinical Medicine, 7, 210-219. https://doi.org/10.4236/crcm.2018.73018