Background: Self-medication is the selection and use of medicines by individuals to treat self-recognized illnesses or symptoms without any medical supervision. It resulted in wastage of resources, increases in resistance of pathogens, and causes health hazards such as adverse drug reactions, prolonged suffering and drug dependence. Despite this fact, studies on the subject matter indicated that health science students continued to practice & recommend self-medication to society. Accordingly, the purpose of this study was to estimate the prevalence of self-medication among students of Arsi University College of Health Science and investigate factors associated with it. Methods: A cross-sectional quantitative study with three months illness recall was conducted in Arsi University College of Health Science students from January to February 2015. Data were collected randomly from each department using self-administered questionnaires. Data entry was made using Epi-Info version 3.5.2 and analysis was done using SP SS IBM version 20. Results: From a total of 575 questionnaires distributed, 548 questionnaires with a response rate of 95.30% were collected back assessed as complete, 70.8% (388/575) reported at least one episode of an illness during three months prior to the day of the questionnaire, and 77.10% (299/388) of them accessed to and practiced self-medication during the study period. Students reported for the study period commonly perceived illnesses such as headache 169 (46.50%), gastrointestinal disease 102 (34.10%) and respiratory tract infection 95 (31.80%) accessed mainly antibiotics 179 (59.90%) and analgesics 143 (47.80%) mostly from drug retail outlets 184 (61.50%). The odds of being female university student was 2 fold accessed self-medication than their counter part males with Adjusted Odds Ratio (AOR) 1.84 with 95% Confidence Interval (CI): 1.01 - 3.34, p = 0.046. With regards to field of studies, students of midwifery were 3 folds accessed self-medication than their counter part students of medicine (AOR 2.78; 95%CI = 1.03, 7.39, p = 0.043). Those students who accepted self-medication for low income segment of the population 2 folds accessed self- medication than their counter part who disagree (AOR 1.76; 95%CI = 1.02, 3.06, p = 0.04). The major reasons indicated for self-medication by respondents were perceived mildness of their illness 132 (44.1%), poor quality of routine health care services 81 (27.1%) and it saves their time 60 (20.3%). Most respondents had a positive attitude towards practicing self-medication as especially, they believed a prospective health professionals & low income segments of the populations have a right to practice self-medication ( p < 0.05). Conclusions: Significant numbers of students were self-medicated in this study with antibiotics as major accessed drugs. Being female was significantly associated with self-medication. Conducting tailored behavioral change communication by the health authorities, universities and other stakeholders is recommended.
The World Self-medication Industry defines self-medication as the treatment of common health problems with medicines especially designed, labeled and approved for use without medical supervision [
Several studies revealed that inappropriate self-medication results in wastage of resources, increases resistance of pathogens and generally entails serious health hazards such as adverse drug reactions, prolonged suffering and drug dependence. It also cause incorrect manner of administration, incorrect choice of therapy & masking of severe disease [
A study conducted in Jimma University showed that 45.9% of the students with perceived illnesses practiced self-medication [
Thus, it is important to know the prevalence, and risk factors associated with access to and practice towards self-medication among the various segments of the community to devise appropriate educational, regulatory and administrative measures in alleviating the public health risks arising from improper practices of self-medication. No data is available on the current status of access to and practice towards self-medication among health sciences students of Asella Campus of Arsi University which the current study aimed to generate. The study also provide baseline data to assist different governmental & non-governmental institutions in establishing appropriate evidence to promote rational use of prescription and non-prescription medicines and to promote visiting to health facilities for any self-unlimited and serious conditions.
A cross sectional quantitative study with three months illness recall was conducted in Arsi University College of Health Science regular students from January to February 2015 G.C.
Arsi University is one of the youngest higher education institutions in Ethiopia and established in 2014 by Council of Ministers. Before it became an independent university it was a branch campus of Adama Science & Technology University with two schools previously known as school of Health Sciences and school of Agriculture located at Asella city. Currently Arsi University has five colleges, one school, one institute and one academy. The Health Science College had begun its academic service by enrolling 100 Medicine students. Currently, there are total of 627 Medicine, 106 Public Health Officer, 102 Clinical Nursing, 143 Midwifery and 13 Anesthesia students at different level of year of study.
Stratified sampling technique was employed based on field of studies and their academic year. All department of Arsi University College of Health Science were listed. The departments were again stratified in to different years of study and sections. Population Proportion to Size was allocated the study subject for each stratum. Based on the sampling frame (roster of each department), systematic random sampling techniques was employed to identify each study subject using a sampling interval (k) of 2.
Assumption one: The sample size determination for the first objective (determining prevalence of self-medica- tion) was based similar study taken from Jimma University, the estimate of the prevalence self-medication among the general population (P) of 45.9% [
where, ni = (1.96)2 × 0.459(1 − 0.459)/(0.05)2 = 382.
With population correction formula: n= [ni (1 + (ni/N)], where N = 991 (total number of regular students in Arsi University College of Health Science) this gives us n to 276 and 15% for non-response (refusal to be enrolled and drop outs) makes the sample size 317.
Assumption two: The sample size for the second objective (investigating factors for self-medication) was calculated based two proportions formula [
The data were collected using a structured self-administered questionnaire developed from literature of previous similar studies according to the objectives of the study [
The data collected was checked for completeness and consistency; arrangement was made to enter data after each day field work was completed. Data entry was made using Epi-Info version 3.5.2 (CDC, Atlanta, Georgia, USA) & data analysis was done using Statistical Package for Social Science Research (SPSS IBM Version 20) [
In this study the dependent variable was access to self-medication. For regression analysis accessed self-me- dication coded as “1” and otherwise “0”. The age of students were categorized into two i.e. <=21 and >=22 years. The younger age group was taken as a reference population in the logistics regression analysis. Gender was a nominee variable and males were taken as a reference group. With regards to years of study of students those who are in their sixth years of study scored “0” while the rest lowest achievements get “1”. Similarly, field of studies were considered as independent factor and those students studying medicine got a code “0” while students of Midwifery, Nursing, Public Health Officer and Anesthesia category coded “1”. Students who had a positive attitude towards self-medication for low income segment of the population coded “1” and otherwise “0”. And those students who had a positive attitude towards self-mediation and prospective health care professionals coded “1” and otherwise “0”.
The research proposal was submitted to Research Review Board and ethical clearance was obtained from Addis Continental Institute of Public Health (ACIPH) and Adama Science and Technology University (ASTU). Informed consent was obtained from each study participants after explaining the purpose, objective and benefit of the study for each participant before giving them the questionnaire. Participants were free to withdraw themselves from participation at any time and participant was given the questionnaire privately as much as possible. Participant’s anonymity or confidentiality was maintained.
Of the total of 575 questionnaires distributed to be filled by respondents, 548 were filled collected back and assessed as complete, which gives the response rate of 95.3%. While, 27 (4.7%) constitutes incomplete, refusal & reluctant responses.
Sex, age, department and study year distribution of those who had episodes of illnesses in the specified period was shown in
The prevalence of self-medication for this study is P = 77.1%, 95% CI = 73 - 81 that is, of 388 students reported illness, 299/388 were self-medicated.
The most common types of ailments for which the respondents reported to have accessed drugs for self-medica- tion were headache, followed by gastrointestinal, respiratory, menstrual, eye, skin and sexually transmitted diseases with the respective episode prevalence of 169 (56.50%), 102 (34.10%), 95 (31.80%), 28 (29.20%), 67 (22.40%), 52 (17.40%) and 31 (10.40%) (
Drugs or drug groups commonly used for self-medication among 299 students was shown in
Variables | Frequency | Percent |
---|---|---|
Sex | ||
Male | 397 | 72.4 |
Female | 151 | 27.6 |
Age category in years | ||
18 - 21 | 295 | 53.8 |
22 - 30 | 253 | 46.2 |
Department | ||
Medicine | 348 | 64.4 |
Midwifery | 77 | 14.1 |
Public Health | 59 | 11.3 |
Nursing | 58 | 10.6 |
Anesthesia | 6 | 1.1 |
Year of study | ||
First year | 130 | 23.7 |
Second Year | 185 | 33.8 |
Third year | 72 | 13.1 |
Fourth year | 40 | 7.3 |
Fifth year | 62 | 11.3 |
Sixth year | 59 | 10.8 |
Illness during the previous three months | ||
Yes | 388 | 70.8 |
No | 160 | 29.2 |
Have you accessed self-medication* | ||
Yes | 299 | 77.0 |
No | 89 | 23.0 |
NB: *where n = 388.
Variables | Frequency | Percent |
---|---|---|
Illness (indications) for self-medication | ||
Headache/fever | 169 | 56.5 |
Gastrointestinal disease | 102 | 34.1 |
Respiratory tract infection | 95 | 31.8 |
Eye disease | 67 | 22.4 |
Skin diseases or injury | 52 | 17.4 |
Sexually transmitted disease | 31 | 10.4 |
Maternal/menstrual | 28 | 29.2 |
Drugs accessed for self-medication | ||
Antibiotics | 179 | 59.9 |
Analgesics or antipyretics | 143 | 47.8 |
Gastrointestinal drugs | 86 | 28.8 |
Respiratory tract infection drugs | 74 | 24.7 |
Vitamins | 66 | 22.1 |
ORS | 50 | 16.7 |
NB: Numbers do not add to 100% as patients might have more than 1 choice.
Most of the drugs for self-medication were obtained from drug outlets 184 (61.50%), shop/supermarkets 89 (29.80%), relatives/friends 72 (24.10%) and left over from previous drugs 57 (19.1%). The study participants were asked about their source of information on self-medication and almost half 154 (51.5%) students learned self-medication from own experience, followed by 98 (32.8%) advise form pharmacy professions (
Characteristics | Category | Self-Medication | Crude OR | 95%CI | P-Value | |
---|---|---|---|---|---|---|
Yes (%) | No (%) | |||||
Sex | ||||||
Female | 96(85.0%) | 17(15.0%) | 2.00 | (1.12, 3.58) | 0.019 | |
Male | 203(73.8%) | 72(26.2%) | 1 | |||
Age | ||||||
>=22 | 126(73.7%) | 45(26.3%) | 0.712 | (0.44, 1.15) | 0.161 | |
<=21 | 173(79.9%) | 44(20.3%) | 1 | |||
Field of study | ||||||
Midwifery | 43(89.6%) | 5(10.4%) | 3.02 | (1.15, 7.96) | 0.025 | |
Nursing | 35(87.5%) | 5(12.5%) | 2.46 | (0.92, 6.55) | 0.072 | |
Public health | 34(72.3%) | 13(27.7%) | 0.92 | (0.46, 1.85) | 0.813 | |
Anesthesia | 2(66.7%) | 1(33.3% | 0.70 | (0.06, 7.88) | 0.775 | |
Medicine | 185(74%) | 65(26%) | 1 | |||
Year of study | ||||||
First | 78(82.1%) | 17(17.9%) | 1 | |||
Second | 103(74.6%) | 35(25.4%) | 0.64 | (0.34, 1.23) | 0.18 | |
Third | 39(76.5%) | 12(23.5%) | 0.71 | (0.31, 1.63) | 0.417 | |
Fourth | 22(66.7%) | 11(33.3%) | 0.44 | (0.18, 1.07) | 0.069 | |
Fifth | 26(76.5%) | 8(23.5%) | 0.71 | (0.27, 1.83) | 0.477 | |
Six | 31(83.8%) | 6(16.2%) | 1.13 | (0.41, 3.12) | 0.819 | |
Self-medication is accepted for low income segment of population | ||||||
Agree | 106(82.8%) | 22(17.2%) | 1.67 | (0.98, 2.86) | 0.06 | |
Disagree | 193(74.2%) | 67(25.8%) | 1 | |||
Health science students have the right to self-medicate | ||||||
Agree | 191(77.3%) | 56(22.7%) | 1.04 | (0.64, 1.70) | 0.869 | |
Disagree | 108(76.6%) | 33(23.4%) | 1 |
to be self-medicated three times greater than other departments (COR = 3.20; 95% CI = 1.15 - 7.96, P = 0.025). Whereas self-medication was not statistically significantly associated with year of study (P > 0.05) (
Since factors like sex, age, field of study and attitude toward self-medication (Self-medication is accepted for low income) has P-value less than or equal to 0.2, a multivariate analysis was then carried out to evaluate the effect of adjusted variables on each other against the dependent variable. The odds of being female university student was 2 fold accessed self-medication than their counter part males with Adjusted Odds Ratio (AOR) 1.84 with 95% Confidence Interval (CI) : 1.01 - 3.34, P = 0.046. With regards to field of studies, students of midwifery were 3 folds accessed self-medication than their counter part students of medicine (AOR 2.78; 95%CI = 1.03, 7.39, P = 0.043). Those students who accepted self-medication for low income segment of the population 2 folds accessed self-medication than their counter part who disagree (AOR 1.76; 95%CI = 1.02, 3.06, P = 0.04) (
Characteristics | Category | Self-Medication | COR | 95%CI | AOR | 95%CI | P-Value |
---|---|---|---|---|---|---|---|
Yes (%) | |||||||
Sex | |||||||
Female | 96 (85%) | 2.00 | (1.12, 3.58) | 1.84 | (1.01, 3.34) | 0.046 | |
Male | 203 (73.8%) | 1 | 1 | ||||
Age group (in years) | |||||||
>=22 | 126 (73.7%) | 0.712 | (0.44, 1.15) | 0.80 | (0.47, 1.34) | 0.41 | |
<=21 | 173 (79.9%) | 1 | 1 | ||||
Field of study | |||||||
Midwifery | 43 (89.6%) | 3.02 | (1.15, 7.96) | 2.76 | (1.03, 7.39) | 0.043 | |
Nursing | 35 (87.5%) | 2.46 | (0.92, 6.55) | 1.98 | (0.72, 5.45) | 0.188 | |
Public Health | 34 (72.3%) | 0.92 | (0.46, 1.85) | 0.82 | (0.39, 1.76) | 0.937 | |
Anesthesia | 2 (66.7%) | 0.70 | (0.06, 7.88) | 0.91 | (0.08,10.33) | 0.937 | |
Medicine | 185 (74%) | 1 | 1 | ||||
Self-medication is accepted for low income segment of the population | |||||||
Agree | 106 (82.8%) | 1.67 | (0.98, 2.86) | 1.76 | (1.02, 3.06) | 0.044 | |
Disagree | 193 (74.2%) | 1 | 1 |
NB: COR: Crude Odds Ratio; AOR: Adjusted Odds Ratio; CI Confidence Interval.
Although responsible self-medication is the practice whereby individuals treat their ailments and conditions with medicines which are approved and available without prescription, and which are safe and effective when used as directed, it will lead to unintended effect if inappropriately used. The result from this study revealed that the prevalence of self-mediation among students reported illness was 299 (77.10%) which was similar to the study conducted in India with prevalence of 78.62% [
The data from the present study indicated that sex had a significant independent association with the practice of self-medication that is females were more inclined to self-medication than men (P < 0.05) which was similar to studies conducted Mekele [
Despite the fact that the respondents’ level of education and field of study were not significant factors in the bivariate analysis (but the result revealed self-medication was significant for midwife students P < 0.05 and the percentage of self-medication was lower as year of study increased i.e. gaining more clinical and drug knowledge may contributed for this result). The study conducted in Mekele & Gondar [
Headache, a predisposing factor, was the primary symptoms for practicing self-medication 169 (56.50%) which were supported by the study elsewhere reported 60% in Addis Ababa town [
Non-seriousness of the illness & saving time was the two major reasons of self-medication in this study. This result was expected as university students are busy of learning activities. So the university clinic needs to find ways by which it will decrease waiting time to see physicians. Factors like emergency use, cost, prior experiences, and knowledge of pharmacology & service quality are frequently reported in literature and different surveys [
Drug consumers were asked as to their source of advice/information for self-medication. The results revealed that the major source for self-medication were their own experience & advice of the pharmacy professionals but without formal prescription. Other studies carried out in India reported that the three most important sources of drug information among all students were books, family members and seniors &friends [
In this study most of drugs were accessed from drug outlets (61.5%). Drugs retail outlets (40.40%); relative/ friends (15.63%) and open market (14.10%) were reported in a similar study done in Mekele University [
The study revealed that 238 (79.60%) of self-medicated students were able to recall the name of drug(s) they used which was higher than the study done in Jimma town 73.8% [
Our study revealed thatantibiotics (59.90%), analgesics (47.80%), gastrointestinal drugs (28.80%) and respiratory drugs (24.70%) were the mostcommon self-medicated group of drugs. Other similar studies carried out in India reported that 91% analgesics while 53.5% antibiotics [
Finally, the study result revealed that from all respondents participated in the study, 347 (63.30%) of students believe that “Students of health science have the right to prescribe medicine for their own consumption” and 358 (65.30%) students believed that self-medication is the accepted way of addressing health problems for low income segment of the population (P < 0.05) , this might be a means for drug interaction with regular medicine, drug resistance for antimicrobials, masking and complication of illnesses and increase irrational use of medicines.
In conclusion, a significant number of students, 77.1%, accessed to and practiced self-medication among those reported illness during the study period. Female university students had more practice of self-medication than their counter part males. Headache and gastrointestinal disease were the most commonly reported conditions for self-medication practices in the current study. Antibiotics and analgesics were the most commonly reported types of medications consumed in self-medications, drug retail outlets were the major sources of drugs and contributed to increasing practice for self-medication. The major reasons indicated for self-medication by respondents were their perceived towards their illness as it is mild, the quality of health care at university clinics is poor and self-medication saves their time. Most respondents believed to practice self-medication as they are health professionals & also they considered it as right to practice for low income segments of the populations. Finally, to address this high prevalence of self-medication and promote rational drug use among university health science students, conducting tailored behavioral change communication strategies by the health authorities, universities and other stakeholders is recommended. In addition, the gender difference observed in this study, investigators recommended an exploratory qualitative research.
This study is limited to self-medication practice to group/class of drugs. It didn’t include each drugs used for self-medication. The questionnaire is self-reported one which may lead to under or over reporting.
The authors would like to thank respondents of the survey who voluntarily took part in this study. The authors also extend their gratitude for Wondossen Gadisa for his effort in coordinating the data collection.
The author(s) declare that they have no competing interests.
The authors responsible were SAB, MDA & AWY. SAB have made substantial contributions to conception and design, or acquisition of data, or analysis and interpretation of data. MDA have been involved through the whole process of this research activity. AWY have been involved in revising it critically for important intellectual content. MDA the corresponding author submitted the paper for publication.
Shimelis Adugna Bekele,Mesele Damte Argaw,Alemayehu Worku Yalew, (2016) Magnitude and Factors Associated with Self-Medication Practices among University Students: The Case of Arsi University, College of Health Science, Asella, Ethiopia: Cross-Sectional Survey Based Study. Open Access Library Journal,03,1-15. doi: 10.4236/oalib.1102738
Self-Administered Questionnaire
Instructions:
This is the questionnaire of the self-medication practice study you’ve been kind enough to participate in. We ask you to please fill out this questionnaire made of two sections. The first parts are general information about your profile. Then, there is an entire section about your self-medication practice in the last three months. The results of the study would be used to identify the gaps with regard to self-medication practice so please fill the questioner appropriately.
Your answers are absolutely confidential. They will be seen only by people held to professional secrecy, and the information will be treated anonymously. Please answer the questions in the order they’re given; at the bottom of each page check if you’ve answered them all before you turn the page.
If you feel tired, take a short break. If something is not clear, don’t hesitate to ask for an explanation from the person who gave you the questionnaire.
Section I. Demographic characteristics of the respondents.
Section II. Prospective of Self-Medication.
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