| Gene cluster | Full product conserved in produce-associated outbreak strains (AA/AA) | Product |
| ehxD | Lys208Ile | hemolysin transport protein |
| ehxA | Glu157Ala | enterohemolysin (EHEC hemolysin) |
| espY4 | Ile379Thr & Pro397Ser | non-LEE-encoded type III secreted effector |
| nleG5-1 | Pro11Ser & Pro204Lys | non-LEE-encoded type III secreted effector |
| nleG6-1 | 8 AA changes | non-LEE-encoded type III secreted effector |
| espY1 | 5 AA deletion | non-LEE-encoded type III secreted effector |
| csgG | Pro76Thr | curli production assembly/transport component, 2nd curli operon |
| ykgA | Thr187Ile | predicted DNA-binding transcriptional regulator |
| ycbF | Arg60Ser | |
| ydeA | Trp360Leu | predicted arabinose transporter |
| eivF | His163Gln | putative regulatory protein for type III secretion apparatus |
| stx1A | Absent | shiga-like toxin 1 subunit A |
| stx1B | Absent | shiga-like toxin 1 subunit B |
| stx2Bc | Present | shiga-like toxin2c subunit B |
| espJ | mutation leads to a premature stop codon at position 181AA/217AA | translocated type III secretion system effector |