| Gene cluster or operon | Product | Reference |
| Interaction with host factors stcE | Zinc metalloprotease | [61] [102] |
| espP | Serine protease | [62] |
| ehxC | acyltransferase | [65] |
| ehxA | enterohemolysin (EHEC hemolysin) | [65] |
| ehxB | ABC transporter ATPase | [65] |
| ehxD | hemolysin transport protein | [65] |
| chuS | heme oxygenase | [67] |
| chuA | outer membrane heme/hemoglobin receptor | [67] |
| TolC | Transport channel | [63] |
| sapABCDF | ||
| sapA | predicted antimicrobial peptide transporter subunit | [68] |
| sapB | predicted antimicrobial peptide transporter subunit; membrane component of ABC superfamily | [68] |
| sapC | predicted antimicrobial peptide transporter subunit; membrane component of ABC superfamily | [68] |
| sapD | peptide transport system ATP-binding protein | [68] |
| sapF | peptide transport system ATP-binding protein | [68] |
| afuABC | ||
| afuA | periplasmic ferric iron-binding protein | [64] |
| afuB | putative permease component of transport system for ferric iron | [109] |
| afuC | putative ATP-binding component of a transport system | [109] |
| L7004 | putative hemolysin expression modulating protein | [5] |
| kdtA | 3-deoxy-D-manno-octulosonic-acid transferase (KDO transferase) endotoxin system | [105] |
| Island with iron transport cluster | ||
| Z4382 | putative iron compound-binding protein of ABC transporter family | [5] |
| Z4383 | putative iron compound permease protein of ABC transporter family | [5] |
| Z4384 | putative iron compound permease protein of ABC transporter family | [5] |
| Z4385 | putative ATP-binding protein of ABC transporter family | [5] |
| Z4386 | putative iron compound receptor | [5] |
| Survival through host defense barriers | ||
| katP | bifunctional catalase/peroxidase | [80] |
| terZABCDEF | ||
| terZ | putative phage inhibition, colicin resistance and tellurite resistance protein | [78] |
| terA | putative phage inhibition, colicin resistance and tellurite resistance protein | [78] |
| terB | putative phage inhibition, colicin resistance and tellurite resistance protein | [78] |
| terC | putative phage inhibition, colicin resistance and tellurite resistance protein | [78] |