A. K. Zhanataev et al. / HEALTH 2 (2010) 412-417
Copyright © 2010 SciRes. http://www.scirp.org/journal/HEALTH/
417
417
the analysis, despite obvious tendencies.
Continuing studies with a larger number of patients
are required. Our results underscore the need to use the
comet assay in two variants, the alkali and the neutral
assays that allows a more complete study of DNA dam-
age. Also, parallel analysis of plasma/serum DNA and
DNA repair rate of oxidative DNA damage may help
evaluate interrelations of different factors and its role in
cellular death mechanisms and development MOF.
Openly accessible at
In conclusion, blood cells from severe trauma pa-
tients’ display increased DNA damage associated with
apoptosis and necrosis. Reduced plasma TAOS and a
tendency to increase of 8-oxoguanine in DNA was ob-
served.
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