ABSTRACT

Birth of preterm infants is a stressful event for their parents, particularly for mothers. The mothers of preterm infants often feel hard to relate their infants because they have separated since their first days after delivery. Long term separation and less attractive, less responsive appearance of preterm infants also make it difficult to build mother-child relationships. In addition, the mothers of preterm infants are likely to have mood disorders such as depression, anxiety, and stress-related disorders. The mothers’ psychiatric illnesses affect the psychosocial development of preterm infants and are often regarded as a risk factor for child abuse and maltreatment in later life. Child abuse and maltreatment are also prevalent among preterm infants than the full term infants. Intervention from the early period of preterm birth is an important issue for both preterm infants and their mothers. Medical and co-medical professionals should pay attention to developmental outcome of preterm as well as psychosocial conditions of their mothers for the improvement of their mental health.

1. INTRODUCTION

Advances in neonatal medicine have improved survival rates and enabled the intact survival of preterm infants, even of extremely low birth weight infants (birth weight < 1000 g). However, many potential risk factors are associated with further development of preterm infants, e.g., periventricular hemorrhage, ventricular dilation, periventricular leukomalacia, chronic neonatal lung diseases, history of infection, male gender, and being small for gestational age [1-4]. In addition to physical sequelae, emotional problems of their mothers and quality of parenting behavior may also affect the psychosocial and cognitive development of preterm infants [5-10]. With improved survival chances of preterm infants, there is growing concern for their developmental outcome and future quality of life.

The increase in survival rate of preterm infants raised the mental health problems of the infants and their mothers which have not been experienced before. That is the psychological interaction between survived infants grows with the problem of developmental deviation or delay and their mothers who often becomes depressed by blaming herself for not having given birth to a healthy baby. Therefore, to describe the situation of preterm infants and their mothers in early period after delivery and to discuss the early intervention to prevent or improve mood disturbances of the mothers appear to be important in terms of maternal and child mental health.

2. IMPORTANCE OF MENTAL HEALTH OF MOTHERS AND THEIR PRETERM INFANTS

Preterm infants or those with severe physical problems are obliged to spend the postnatal period in an incubator for various medical reasons and are thus separated from their mothers for a prolonged period of time. Medical care for premature infants naturally has its main focus on the infant’s physical health, as provided by the neonatal intensive care unit (NICU). For parents of premature infants, not only psychological damage due to preterm delivery but also the NICU environment appears to be stressful with bright lights, noisy life support and monitoring equipment, and chemical scents [11]. Furthermore, viewing their ill infant connected to equipment by tubes and wires and surrounded by medical personnel can be very disturbing [11].

However, the greatest source of stress experienced by these parents is often the loss of their expected and desired parental role. Emotional reactions of parents to the NICU experience can vary from disappointment, guilt, sadness, depression, hostility, anger, fear, anxiety, grief, and loss of self-esteem [12-15]. After the birth of a premature infant, high levels of depression and anxiety are common in both parents [13,16]. In particular, for mothers, the experience of preterm birth is regarded as a highly stressful event, and they may find it more difficult to establish relationships with their babies after being separated from them during the initial days following delivery [17]. They tend to blame themselves for not having given birth to a healthy baby and self reproach that they caused their infants to go through painful treatment and for being unable to do anything for the child [18].

Even 1 month after birth, mothers of premature infants have been found to be at a greater risk of psychological stress than mothers of full-term infants, with 10% of the former experiencing severe symptoms of psychological distress neonatally and one-third experiencing clinical levels of depression and anxiety [15]. We and others have further confirmed that an admission of infants to NICU increased the prevalence of mood disturbance in their mothers [19,20]. Furthermore, the mothers of infants in NICU show increased symptoms of acute traumatic stress and depression [21,22]. It has been suggested that a traumatic maternal experience related to premature birth may have a lasting influence on motherchild interactional behavior [23,24].

3. MATERNAL PSYCHIATRIC ILLNESS, PRETERM BIRTH, AND CHILD ABUSE

Maternal depression, anxiety or other psychiatric illness, history of child abuse and mothers’ socioeconomic disadvantages are regarded as risk factors for child abuse and maltreatment [25-28]. Previous studies have consistently found a high incidence of child abuse associated with a history of neonatal medical problems, premature birth, and low birth weight. About the relation between a premature infants and a child abuse, it goes back to prospective study in 1970’s. Hunter et al. [29] reported the high incidence of maltreatment in the preterm and ill newborns and showed significant association between social isolation, a family history of child abuse and neglect, serious marital problems, inadequate child care arrangements, apathetic and dependent personality styles, and inadequate child spacing with later maltreatment. Bugental et al. [26] suggested that child maltreatment during the 1st year of life was predicted by neonatal status, such as low Apgar scores, preterm status.

Mothers delivering preterm infants are likely to have had physical or psychosocial vulnerabilities before their pregnancy. Lower socioeconomic status, poverty, minority status, substance abuse, psychiatric illness, history of child abuse, or various physical comorbidities exist in expectant mothers of preterm infants before and during pregnancy and continue to exist after birth. These unresolved problems often persist and affect parenting behavior; child abuse and maltreatment are serious problems in preterm infants.

Another explanation for the higher prevalence of child abuse and maltreatment in preterm infants involves the relationships between neonatal problems and adverse parenting behavior, causing possible delay or disturbance in the bonding process between the parent and infant [24]. According to Tooten et al. [11], “at the appearance of preterm infants is judged as less attractive than full term infants and their behavior is observed as less alert, less attentive, less active and less responsive than that of full-term infants. Furthermore, preterm infants engage in fewer broad smiles, are relatively fussy and irritable, are more difficult to soothe, show more mixed behavioral cues, show more sensory-defensive behaviors and are described as more temperamentally difficult than term peers”. It is established that mothers find it more difficult to relate to infants from they have been separated during their first days following delivery. Size, appearance and responsiveness may also influence the mother’s first feeling about the infants [19,30].

 Parental “bonding” can be described as “the establishment of an emotional connection of the parent to the infant [31]”. The process of forming a bond with an infant begins during pregnancy and develops further after birth, and the process of bonding, in turn, sets the stage for the evolvement of attachment, which develops later in childhood and can be described as “the capacity to form selective, enduring and mutual relationships [11].” In case of premature birth, the process of bonding may be disturbed because the mother is often separated from the infant while medical treatment is provided. Negative parental feelings may impede the establishment of a wellbalanced parent-infant relationship and can be the source of parent-infant attachment difficulties [18]. Both maternal emotional illness and the lower sensitivity of infants may disturb healthy bonding and attachment between mothers and their infants.

4. EARLY INTERVENTION IN REGARD TO MENTAL HEALTH OF MOTHERS OF PRETERM INFANTS

Because both preterm birth itself and adverse parenting behavior due to mothers’ psychosocial stress may increase the risk of child abuse and maltreatment in preterm infants, early intervention to reduce maternal psychosocial burden would improve child health. Intervention programs for mothers of preterm infants include psychological support, health check-ups for the childand stabilization of mother-infant relationships [13,14, 31-35]. These trials have continued through admission of infants to the NICU, discharge, and return home [36].

As a support measure to establish bonding during hospitalization of infants, skin-to-skin contact [37] such as kangaroo care [38] and touch therapy [39] contribute to the development of a healthy mother-infant relationship. Since a Colombian pediatrician concerned with the problems arising from a shortage in incubators and impact of separating women from their infants in NICU developed Kangaroo care [40], Kangaroo care is widely considered to be the most feasible, readily available, and preferred intervention for decreasing neonatal morbidity and mortality in developing countries. This method aims to restore the close relationship between the newborn and parents by placing the infant in direct skin-to-skin contact with one of them, ensuring physiological and psychological warmth and bonding. The kangaroo position provides ready access to nourishment; while the parent’s stable body temperature helps regulate the neonate’s temperature more smoothly than an incubator and enables readily accessible breastfeeding [40]. In the case of preterm infants, this technique not only stabilizes physical condition and breast feeding but also reduces infants’ pain perception and stabilizes mothers’ mood status [41- 47].

Touch therapy [39], another type of skin-to-skin contact, is used to heal the infant, where the mother’s hands are the instrument. It is reported that touch therapy is effective in stabilizing physical status, promoting gain in body weight, and shortening admission reducing stress behavior in preterm infants treated in the NICU [48,49]. Both Kangaroo care and touch therapy are only feasible after the medical condition of the infants is no longer life-threatening. In case of ELBWIs in incubator, a preparatory process before touch therapies is applied that the mother gently cradle their child’s head and hips, which is termed “preliminary holding”. The implementation of preliminary holding helps mothers become familiar with their infants, reduce distress, and grow into motherhood [18]. Skin-to-skin contact such as Kangaroo care, touch therapy and preliminary holding are applicable to infants in the NICU, and these enhance the establishment of a healthy mother-child relationship in the early period after the birth of a preterm infant.

After discharge of an infant from the NICU, various levels of child support are available, such as peer groups, individual counseling, and home visits. Early individualized, family-based interventions during neonatal hospitalization and the transition to home have been shown to reduce parental stress and depression, increase parental self-esteem, and improve positive early parent-preterm infant interactions [50]. Ravn et al. [51] reported early interaction-based interventions on parenting and infant communication skills reduced postpartum depression and extended the period of breastfeeding. Preyde a et al. [14] suggested that parent-to-parent peer support for mothers of very preterm infants in a NICU effective in helping mothers deal with the stress of very preterm birth. During hospitalization, parental self-confidence has to be repetitively reinforced and evaluated before discharge because insecure parents at discharge are more likely to have problems with their infants at home, which may lead to persistent parent-infant relationship problems [11].

Furthermore, as a new trial, the usefulness of “prenatal visiting” is also reported [52]. Before delivery, expectant mothers of premature infants often have psychological problems such as feelings of anxiety or depression because they are afraid of miscarriage, stillbirth, or preterm birth. Admission of newborn infants to the NICU may also increase the prevalence of mood disturbance in their mothers, who then experience preterm birth as a highly stressful event. The implementations of “prenatal visiting” help mothers relax, become familiar with their infants, reduce their sense of guilt, and increase confidence in their motherhood skills and their ability to take care of their infant. These may also improve mother-child communication and interaction and yield positive consequences for the families of preterm infants in their future life together.

5. SUMMARY

Birth of preterm infants is very stressful for the mother and often causes psychiatric disorders. Early intervention is essential for improvement of the mother’s mental health, establishment of mother-child relationships, cognitive development of the child, and prevention of child abuse and maltreatment.

REFERENCES